Seminar Series

"A Precision Medicine Approach to Smoking Cessation Among Native Americans"

PRECISION MEDICINE SEMINAR SERIES

October 5, 2018 | 2:00 to 3:00 p.m. | 1-451 Moos Tower

Dr. Dana Mowls Carroll is a postdoctoral fellow in the Tobacco Research Programs at the University of Minnesota, led by Masonic Cancer Center member Dr. Dorothy Hatsukami. Her research interests are in tobacco-related disparities, cancer prevention, and tobacco regulatory science. She received a Ph.D. in epidemiology from the University of Oklahoma Health Sciences Center in 2017. She aims to direct an independent research group that contributes to the reduction of tobacco-related morbidity and mortality with a special emphasis on populations that bear the greatest burden—populations that are often understudied and historically underserved. Her presentation will provide an overview of a Minnesota Precision Medicine Collaborative project which seeks to increase access to precision medicine approaches to smoking cessation in the Native American population in Minnesota.

"International Efforts in Transplantation Genomics: Large Research Cohorts"

PRECISION MEDICINE SEMINAR SERIES

September 7, 2018 | 2:00 to 3:00 p.m. | 1-451 Moos Tower

Brendan Keating, D.Phil., studied molecular genetics at the Department of Clinical Medicine at University of Oxford, with his Ph.D. lab work completed in the Wellcome Trust. He completed a post-doctoral fellowship at the Institute of Translational Medicine and Therapeutics at UPenn, and was a visiting Scientist at the Wellcome Trust Sanger Institute. Dr. Keating designed and developed genomic tools for cardiovascular-related studies that have been used in over 200,000 DNA samples across 60 studies. His major research interests focus on the analyses of miRNA, mRNA and polymorphisms of donor and recipients genomes in heart, liver, lung and kidney transplantation, with the aim of delivering individualized treatment of immunosuppression therapies, and detection of genetic signals that underpin graft rejection and complications of rejection. Dr. Keating is Principal Investigator of genome-wide association studies for solid-organ transplant studies within the Children’s Hospital of Philadelphia. He is also a member of the pharmacogenomics and return of results working groups of the NHGRI electronic medical record and genomics (eMERGE) network, which is integrating clinical genetic data into patient’s electronic medical records for clinical decision support in the individualized dosing of patients for a range of therapeutics.

"Genetic Basis for Brain Size in Human Development"
 

PRECISION MEDICINE SEMINAR SERIES

June 1, 2018 | 2:00 to 3:00 p.m. | 1-450 Moos Tower

Dr. Dobyns is Professor of Pediatrics (Genetics) and Neurology at the University of Washington, and Principal Investigator in the Center for Integrative Brain Research at Seattle Children's Research Institute. He is a physician-scientist trained in both Pediatric Neurology and Medical Genetics, and Director of a molecular genetics laboratory that studies the nature and causes of numerous developmental brain disorders in children.

While best known for studies of lissencephaly, his work has involved many different disorders including early childhood epilepsy, intellectual disability, autism, microcephaly and macrocephaly, many malformations of cortical development, malformations of the corpus callosum, brainstem and cerebellum, vascular malformations both in the brain and elsewhere, childhood stroke, and mosaicism as a mechanism of disease. 

"Panel Discussion: A Vision for Precision Medicine in the AHC"

PRECISION MEDICINE SEMINAR SERIES

February 2, 2018 | 2:00 to 3:00 p.m. | 1-450 Moos Tower

Panelists:

Jakub Tolar, MD, PhD—Dean, Medical School; Interim Vice President for Health Sciences, AHC; Director, Stem Cell Institute; Distinguished McKnight Professor of Pediatrics, University of Minnesota

Pamala Jacobson, PharmD—Director, Institute of Personalized Medicine; Professor of Experimental and Clinical Pharmacology, University of Minnesota 

Chad L. Myers, PhD—Associate Professor of Computer Science & Engineering, University of Minnesota

Clifford Steer, MD—Associate Dean for Industry Partnerships, Medical School; Professor of Medicine, Gastroenterology Hepatology and Nutrition; Professor of Genetics, Cell Biology and Development, University of Minnesota 

Brian Van Ness, PhD—Professor of Genetics, Cell Biology and Development, University of Minnesota

"Implementation of Clinical Pharmacogenomics at Children’s Minnesota"
 

PRECISION MEDICINE SEMINAR SERIES

December 1, 2017 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

David Gregornik is the Pharmacogenomics Program Leader at Children’s Minnesota. Dr. Gregornik earned his bachelor of science and his PharmD from the University of Minnesota College of Pharmacy. In 1995 he completed a specialty residency in pediatric pharmacotherapy at St. Jude Children’s Research Hospital in Memphis; he subsequently joined the staff of the pharmaceutical department, providing advanced clinical pharmacy care to children with cancer and undergoing bone marrow transplant. In 2009, he moved to Memorial-Sloan Kettering Cancer Center where he served as manager of pediatric clinical pharmacy programs. In 2013 he returned to St. Jude where he worked with his colleagues to establish a clinical pharmacogenetics service. Dr. Gregornik joined Children’s Minnesota in August 2016.

"Health Informatics to Facilitate Precision Medicine"

PRECISION MEDICINE SEMINAR SERIES

October 6, 2017 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

Dr. Zhang is an Assistant Professor at the Department of Pharmaceutical Care & Health Systems, the Institute for Health Informatics, and the Data Science graduate program. He obtained his PhD in Health Informatics at the University of Minnesota. He has extensive research experience in the field of health and biomedical informatics, especially clinical natural language processing (NLP), biomedical text mining and translational informatics. His research interests include the secondly analysis of electronic health record (EHR) data for improving quality of patient care as well as discovery of pharmacovigilance knowledge through mining a large scale of biomedical literature. Dr. Zhang is the Principal Investigator on a NIH/NCCIH R01 research award entitled “An Informatics Framework for Discovery and Ascertainment of Drug-Supplement Interactions." His work on discovery of drug-supplement interactions has been highlighted by The Wall Street Journal and Fox News.

"Pharmacogenomics-Guided Antidepressant Treatment for Major Depressive Disorder -- A Systematic Review"

PRECISION MEDICINE SEMINAR SERIES

September 1, 2017 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

Eric Dieperink received his Bachelor of Science in Molecular Biology from the University of Wisconsin-Madison. He graduated from the University of Minnesota Medical School and completed his psychiatric residency at the University of Colorado Health Sciences Center. He is currently a staff psychiatrist at the VA Medical Center in Minneapolis. His primary area of research has been alcohol use and depressive disorders.

"There and Back Again: A Molecular Pathologist’s Perspective on Developing NGS-based Clinical Oncology Diagnostics"

PRECISION MEDICINE SEMINAR SERIES

January 5, 2018 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

Andrew Nelson is an Assistant Professor in the Department of Laboratory Medicine and Pathology at the University of Minnesota. He is an anatomic and molecular genetic pathologist and a member of the Division of Molecular Pathology and Genomics. He earned his doctoral degree in cancer biology and experimental pathology with a focus on cell signaling mechanisms that regulate the function of BRCA1 and BRCA2 in breast and ovarian cancer. As a member of the Masonic Cancer Center, he collaborates with colleagues in both clinical and basic research projects involving solid tumor molecular diagnostics.

"The Alcohol Flushing Response: Implications for Human Health and Anesthetic Management"
 

PRECISION MEDICINE SEMINAR SERIES

March 2, 2018 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

Eric Gross is an Assistant Professor in the Department of Anesthesiology, Perioperative and Pain Medicine at Stanford University.

Dr. Gross is a physician-scientist and practicing anesthesiologist, and an assistant professor at Stanford University. He is nationally and internationally known for his research in the field of Anesthesiology, particularly on anesthetic and analgesic mechanisms of cellular protection. His research has been continuously funded by the NIH since 2011 and is a recent recipient of a NIGMS MIRA award to study the effects of aldehydes on human health.

"Cardiovascular Epigenomics: From Chromatin Fiber to Human Populations"
 

PRECISION MEDICINE SEMINAR SERIES

April 6, 2018 | 2:00 to 3:00 p.m. | 5-125 Moos Tower

Thomas Vondriska is a Professor of Anesthesiology, Medicine and Physiology at the David Geffen School of Medicine at UCLA. Dr. Vondriska’s laboratory aims to reveal principles of chromatin regulation with the goal of understanding how epigenetics contributes to heart disease in humans. It has trained more than 40 students, fellows and junior faculty. Visit the lab’s website at www.vondriskalab.org.